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Post by billy on Dec 29, 2015 21:44:18 GMT 10
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Post by chopper62 on Dec 29, 2015 22:02:10 GMT 10
It is swabable i believe ?
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Post by billy on Dec 29, 2015 22:29:08 GMT 10
There is a train of thought that if administered too close to Raceday that cobolt levels may be high.
There are also horse and dog people who have been using it for years as a general tonic weekly or bi weekly.
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Post by chopper62 on Dec 29, 2015 22:38:28 GMT 10
Yes that is what i was refering to , used it many yrs ago but not sure i would risk it now l
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Post by billy on Dec 29, 2015 22:43:41 GMT 10
Maybe someone will post the recommended withholding times, I thought I read somewhere it was 96hrs but unless it's official you like me are p*****g into the wind (hope that doesn't offend anyone)
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Post by chopper62 on Dec 29, 2015 22:47:53 GMT 10
Lol you're a sensitive fellow Billy , lol IE : "pissing in wind " ,I think there is something on Fb about Vam on there website ,
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Post by billy on Dec 30, 2015 8:58:46 GMT 10
Compliments of GRNSW
This information is made available to participants, in order to assist them to comply with the rules. The detection times are not withdrawal times and should not be construed as such. There are many relevant factors in relation to any substance that could give rise to unpredictable and prolonged excretion times including:
• An animal’s general health status, its physiology, metabolism, hydration status, fitness level, training regime, nutritional and dietary supplementation and concurrent medical treatment. • Dose rate (i.e. the amount given per kg) – a higher dose will take longer to remove from the body system and could be detrimental to the dog’s health. Combining similar supplements may also increase the dose rate as each may contain cobalt. • Treatment duration and frequency (i.e. how long a supplement is given for and how often) – a cumulative effect could occur where supplements are given for extended periods, particularly when this is against the directions of the manufacturer (‘off-label’). • Route of administration (i.e. orally or by injection) – injection of cobalt supplements will lead to much greater levels of cobalt and therefore requires greater withholding periods prior to racing than orally administered cobalt. Oral administration of some highly concentrated products will still lead to a breach of the cobalt threshold and require an adequate withholding period. • Pharmaceutical preparation (i.e. how much cobalt it contains) – different cobalt salts contain different amount of cobalt. The preparations may also have different properties that result in e.g. different rates of absorption.
Careful consideration of the above factors and adequate veterinary advice is important prior to administering cobalt containing substances, particularly by injection. More conservative withdrawal times may need to be implemented.
The following administration studies were performed on six greyhounds:
VAM® Paste VAM® Paste (CEVA) is a commercially available product registered as a supplement (vitamins, amino acids and minerals) paste. The cobalt salt is cobalt sulfate (240 µg/mL) and contains cyanocobalamin (150 µg/mL). This is equivalent to around 98 µg/mL of cobalt. The manufacturer’s recommended dose rate in dogs is 0.25-1mL per 10kg bodyweight, twice weekly, administered orally.
Dose administered: 1mL/10kg, administered orally on two occasions on alternate days. This is equivalent to a dose rate of 24 µg/kg of cobalt sulfate.
Results: Cobalt levels detected above the 100 ng/mL threshold (maximum 317 ng/mL) for up to 6 hours after the second dose, but did not return to resting levels for 24 hours. A cumulative effect may occur with this product. A minimum withholding period of 24 hours is suggested.
VAM® Injection VAM® Injection (CEVA) is a commercially available product registered as a supplement (vitamins, amino acids and minerals) injection. The cobalt salt is cobalt sulfate (240 µg/mL) and contains cyanocobalamin (150 µg/mL). This is equivalent to around 98 µg/mL of cobalt. The manufacturer’s recommended dose rate in dogs is 0.25-1mL per 10kg bodyweight, twice weekly, administered intramuscularly.
Dose administered: 1mL/10kg, administered intramuscularly on two occasions on alternate days. This is equivalent to a dose rate of 24 µg/kg of cobalt sulfate
Results: Cobalt levels detected above the 100 ng/mL threshold (maximum 6523 ng/mL) for up to 48 hours after the second dose, but did not return to resting levels for at least 72 hours. A cumulative effect may occur with this product. A minimum withholding period of 96 hours is suggested.
Hemo-15® Injection Hemo-15® (Virbac) is a commercially available product registered as a supplement (iron, amino acid and B-vitamin) injection. The cobalt salt is cobalt gluconate (0.7 mg/mL) and contains cyanocobalamin (150 µg/mL). This is equivalent to around 99 µg/mL of cobalt. The manufacturer’s recommended dose rate (in horses) is 1mL per 50kg of bodyweight, administered intravenously.
Dose administered: 1mL, administered intravenously, once per day for three days. This is equivalent to a dose rate of 20 µg/kg of cobalt gluconate, based on a 35kg dog.
Results: Cobalt levels detected above the 100 ng/mL threshold (maximum 1350 ng/mL) for up to 24 hours after the third dose, but did not return to resting levels for 48 hours. A cumulative effect may occur with this product. A minimum withholding period of 48 hours is suggested.
For further information please contact GRNSW.
N.B. Reliance on this communication will not be a defence in the event of a breach of the rules. All participants in races do so subject to, and take full responsibility for their compliance with, the rules which contain, amongst other things, provisions relating to prohibited substances, the disqualification of greyhounds that have been found to have received them and the punishment of those who administer them.
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Post by arakitig on Apr 25, 2019 19:56:58 GMT 10
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Post by exuhuoteqa on Apr 25, 2019 22:00:08 GMT 10
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Post by udonohgukoquj on May 18, 2019 4:06:11 GMT 10
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Post by ifivodix on May 21, 2019 18:49:50 GMT 10
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